Idiopathic pulmonary haemosiderosis in a child with Down's syndrome: case report and review of the literature.
Identifieur interne : 001305 ( Main/Exploration ); précédent : 001304; suivant : 001306Idiopathic pulmonary haemosiderosis in a child with Down's syndrome: case report and review of the literature.
Auteurs : A. Aceti [Italie] ; R. Sciutti ; P R Bracci ; L. Bertelli ; F. Melchionda ; S. CazzatoSource :
- Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG [ 1124-0490 ] ; 2012.
Descripteurs français
- KwdFr :
- Enfant d'âge préscolaire, Femelle, Humains, Hydroxychloroquine (usage thérapeutique), Hémosidérose (), Hémosidérose (diagnostic), Hémosidérose (traitement médicamenteux), Maladies pulmonaires (), Maladies pulmonaires (diagnostic), Maladies pulmonaires (traitement médicamenteux), Résultat thérapeutique, Syndrome de Down (), Tomodensitométrie, Valeur prédictive des tests.
- MESH :
- diagnostic : Hémosidérose, Maladies pulmonaires.
- traitement médicamenteux : Hémosidérose, Maladies pulmonaires.
- usage thérapeutique : Hydroxychloroquine.
- Enfant d'âge préscolaire, Femelle, Humains, Hémosidérose, Maladies pulmonaires, Résultat thérapeutique, Syndrome de Down, Tomodensitométrie, Valeur prédictive des tests.
English descriptors
- KwdEn :
- Child, Preschool, Down Syndrome (complications), Female, Hemosiderosis (complications), Hemosiderosis (diagnosis), Hemosiderosis (drug therapy), Humans, Hydroxychloroquine (therapeutic use), Lung Diseases (complications), Lung Diseases (diagnosis), Lung Diseases (drug therapy), Predictive Value of Tests, Tomography, X-Ray Computed, Treatment Outcome.
- MESH :
- chemical , therapeutic use : Hydroxychloroquine.
- complications : Down Syndrome, Hemosiderosis, Lung Diseases.
- diagnosis : Hemosiderosis, Lung Diseases.
- drug therapy : Hemosiderosis, Lung Diseases.
- Child, Preschool, Female, Humans, Predictive Value of Tests, Tomography, X-Ray Computed, Treatment Outcome.
Abstract
We report the case of a female child with Down's syndrome affected by idiopathic pulmonary haemosiderosis (IPH), who was successfully treated with hydroxychloroquine. First-line conventional treatment of IPH is traditionally based on systemic corticosteroids; however, many steroid-sparing agents are being increasingly used as adjuncts to corticosteroids in children with recurrent or refractory bleeding. The use of these drugs is particularly promising for maintenance treatment, because it tends to avoid the adverse effects of long-term corticosteroids.
PubMed: 23311126
Affiliations:
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Le document en format XML
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Melchionda</name></author><author><name sortKey="Cazzato, S" sort="Cazzato, S" uniqKey="Cazzato S" first="S" last="Cazzato">S. Cazzato</name></author></analytic><series><title level="j">Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG</title><idno type="ISSN">1124-0490</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Child, Preschool</term><term>Down Syndrome (complications)</term><term>Female</term><term>Hemosiderosis (complications)</term><term>Hemosiderosis (diagnosis)</term><term>Hemosiderosis (drug therapy)</term><term>Humans</term><term>Hydroxychloroquine (therapeutic use)</term><term>Lung Diseases (complications)</term><term>Lung Diseases (diagnosis)</term><term>Lung Diseases (drug therapy)</term><term>Predictive Value of Tests</term><term>Tomography, X-Ray Computed</term><term>Treatment Outcome</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Humains</term><term>Hydroxychloroquine (usage thérapeutique)</term><term>Hémosidérose ()</term><term>Hémosidérose (diagnostic)</term><term>Hémosidérose (traitement médicamenteux)</term><term>Maladies pulmonaires ()</term><term>Maladies pulmonaires (diagnostic)</term><term>Maladies pulmonaires (traitement médicamenteux)</term><term>Résultat thérapeutique</term><term>Syndrome de Down ()</term><term>Tomodensitométrie</term><term>Valeur prédictive des tests</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Down Syndrome</term><term>Hemosiderosis</term><term>Lung Diseases</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Hemosiderosis</term><term>Lung Diseases</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Hémosidérose</term><term>Maladies pulmonaires</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Hemosiderosis</term><term>Lung Diseases</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Hémosidérose</term><term>Maladies pulmonaires</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Child, Preschool</term><term>Female</term><term>Humans</term><term>Predictive Value of Tests</term><term>Tomography, X-Ray Computed</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Humains</term><term>Hémosidérose</term><term>Maladies pulmonaires</term><term>Résultat thérapeutique</term><term>Syndrome de Down</term><term>Tomodensitométrie</term><term>Valeur prédictive des tests</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We report the case of a female child with Down's syndrome affected by idiopathic pulmonary haemosiderosis (IPH), who was successfully treated with hydroxychloroquine. First-line conventional treatment of IPH is traditionally based on systemic corticosteroids; however, many steroid-sparing agents are being increasingly used as adjuncts to corticosteroids in children with recurrent or refractory bleeding. The use of these drugs is particularly promising for maintenance treatment, because it tends to avoid the adverse effects of long-term corticosteroids.</div></front></TEI><affiliations><list><country><li>Italie</li></country></list><tree><noCountry><name sortKey="Bertelli, L" sort="Bertelli, L" uniqKey="Bertelli L" first="L" last="Bertelli">L. Bertelli</name><name sortKey="Bracci, P R" sort="Bracci, P R" uniqKey="Bracci P" first="P R" last="Bracci">P R Bracci</name><name sortKey="Cazzato, S" sort="Cazzato, S" uniqKey="Cazzato S" first="S" last="Cazzato">S. Cazzato</name><name sortKey="Melchionda, F" sort="Melchionda, F" uniqKey="Melchionda F" first="F" last="Melchionda">F. Melchionda</name><name sortKey="Sciutti, R" sort="Sciutti, R" uniqKey="Sciutti R" first="R" last="Sciutti">R. Sciutti</name></noCountry><country name="Italie"><noRegion><name sortKey="Aceti, A" sort="Aceti, A" uniqKey="Aceti A" first="A" last="Aceti">A. Aceti</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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